Geographic Distribution of the 20210 G to A Prothrombin Variant
نویسندگان
چکیده
منابع مشابه
Geographic distribution of the 20210 G to A prothrombin variant.
A variant in prothrombin (clotting factor II), a G to A transition at nucleotide position 20210, has recently been shown to be associated with the prothrombin plasma levels and the risk of both venous and arterial thrombosis. The purpose of this study was to investigate the prevalence of carriership of this mutation in various populations. We combined data from 11 centres in nine countries, whe...
متن کاملBranch retinal vein occlusion associated with the 20210 G-to-A prothrombin variant.
PURPOSE To describe a case of branch retinal vein occlusion (BRVO) in a patient who tested positive for the 20210 A allele of the prothrombin (PT) gene. METHODS A 48-year-old man had visual loss in the right eye secondary to BRVO confirmed by ophthalmoscopy and fluorescein angiography. His medical history was not remarkable for common risk factors for retinal occlusive diseases. RESULTS Lab...
متن کاملRAPID COMMUNICATION A Common Prothrombin Variant (20210 G to A) Increases the Risk of Myocardial Infarction in Young Women
Using specimens from a population-based case control The age-adjusted odds ratio for MI was 4.0 (95% confidence study among women ages 18 to 44 years in western Washinterval 1.1 to 15.1). The relative risk was high when another ington, we assessed the relationship between carriership of major cardiovascular risk factor was also present, such as a genetic clotting factor II variant (20210 GrA) a...
متن کاملA common prothrombin variant (20210 G to A) increases the risk of myocardial infarction in young women.
Using specimens from a population-based case control study among women ages 18 to 44 years in western Washington, we assessed the relationship between carriership of a genetic clotting factor II variant (20210 G-->A) and myocardial infarction (MI). The factor II variant was previously shown to be present in 1% to 2% of the population, to increase the levels of factor II, and to be associated wi...
متن کاملReliable genotyping of the G-20210-A mutation of coagulation factor II (prothrombin).
Coagulation Factor II (Prothrombin), Jan Danneberg, André P. Abbes, Ben J. M. Bruggeman, Henk Engel, Jan Gerrits, and Alexander Martens * (Lab. of Clin. Chem., Twenteborg Hosp., P.O. Box 7600, 7600 SZ, Almelo, the Netherlands; Lab. of Clin. Chem., Sophia Hosp., Dr. CA van Heesweg 2, 8025 AB, Zwolle, the Netherlands; *author for correspondence: fax 031-546-833371, e-mail [email protected]...
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ژورنال
عنوان ژورنال: Thrombosis and Haemostasis
سال: 1998
ISSN: 0340-6245,2567-689X
DOI: 10.1055/s-0037-1615049